A 29 year male with chronic kidney disease secondary to NSAID abuse

This is online E log book to discuss our patient’s de-identified health data shared after taking his/her/guardian’s signed informed consent. Here we discuss our individual patient’s problems through series of inputs from available global online community of experts with an aim to solve those patients clinical problems with collective current best evidence based inputs. This e-log book also reflects my patient centered online learning portfolio and your valuable inputs  on comment box is welcome.


I’ve been given this case to solve in an attempt to understand the topic of “patient clinical data analysis" to develop my competency in reading and comprehending clinical data including history, clinical findings, investigations, and come up with diagnosis and treatment plan

A 29 year male agricultural coordinator by occupation came to opd with chief complaints of 
Bilateral pain in lower limbs upto knee since 20 days

HOPI

Patient was apparently asymptomatic 3 years ago then developed severe sudden pain in right lower abdomen for which he went to local hospital and was diagnosed to have renal calculus of 4 - 6 mm & creatinine levels of 6.2 and got treated for it. Both the parameters came down when he got tested later after few weeks.

6 months later patient developed pain in ankle and knees bilaterally, pricking type precipitated by heavy work, relieved by medications for which he visited a local doctor and was tested with high uric acid levels for which he got treated and also got dietary change advice 

followed by this he was intermittently having lower limb pain for which he was having acyclophenac whenever he was having episodes of pain

Since 20 days pain wasn't reliving on medication and he got admitted to a local hospital. his creatinine levels were 8.2 for which he was referred to our hospital for dialysis

No h/o shortness of breath , pedal edema , decreased urine out put , facial puffiness, orthopnea, pnd , chest pain and palpitation


Past history


Right sided renal stone of size 4 - 6 mm for which he got treated medically - 3 years ago

Rat poisoning 6 years ago

Not a known case of diabetes , hypertension ,asthma ,tb, cardiovascular diseases.


Personal history

Diet : mixed
Appetite normal 
Sleep : inadequate  due to pain since 20days 
Bowel and bladder movements regular
No allergies

Occasional alcohol consumption 

Chronic smoker since 6 years ( stopped 8 months back) 


Treatment history


H/o usage of NSAIDs for pain since 2 yrs intermittently




Family history

Not significant 


General examination 

Patient was conscious coherent and cooperative 

pallor present

No icterus cyanosis clubbing lymadenopathy,edema











Vitals 

BP -140/80

RR - 14/min

Temp - 98F 

Pulse rate - 78bpm 

Spo2 98percent 

Grbs - 134 mg%


Systemic examination:


CVS - s1s2 heard no murmurs


Respiratory system

Dyspnoea: No

Wheeze: No

Position of trachea: Central 

Breath sounds: Vesicular 

Adventitious sounds : No


Per abdominal examination

Shape - Scaphoid , inverted umbilicus, no engorged veins, no scars

No tenderness, no palpable mass, No Fluid

No bruits heard

Liver not palpable

Spleen not palpable 

CNS Examination

Conscious coherent cooperative

Higher mental functions intact

No signs of meningitis 

Cranial nerves, motor system, sensory system Normal.

INVESTIGATION 

HIV - non reactive 

HBsAg - negative 

RBS - 114 mg/dl

Blood urea - 176 mg/dl 

Serum creatinine - 7.8mg/dl
















PROVISIONAL DIAGNOSIS 

CHRONIC KIDNEY DISEASE secondary to NSAID abuse 

TREATMENT 

 1) salt restriction <2 g /day 

 2) fluid restriction <1.5L /day 

 3) T.NODOSIS 500mg PO/BD 

 4) T.OROFER-XT PO/OD

 5) T.SHELCAL - CT PO/OD 

 6) T.CAP BIO D3 60,000IU units per weekly 

 7) T.LASIX 10 mg PO/BD 

7) moniter vitals 4 th hrly




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